Mantralayam is a town in Kurnool district in Andhra Pradesh, India. It lies on the banks of the Tungabhadra river which forms the border with neighbouring Karnataka state. It is also called as Manchale. This town is noted for the holy presence of the Vrindavana of Guru Raghavendra Swami, a Madhwa saint and follower of Sri Madhwacharya. It is believed that Guru Raghavendra Swami is in the Vrindavana from the past 337 years and is believed to be in the Vrindavana for another 363 years. While entering the Vrindavana, Guru Raghavendra Swami stated that he would be there (in the Vrindavana) for 700 years.[1]

The nearest railway station is Mantralayam Road, ten kilometres away. This station is on the Guntakal - Raichur railway route. There are frequent bus services from Raichur and Bellary in Karnataka and from Kurnool in Andhra Pradesh. Mantralayam is about 100 km from Kurnool and 250 km from the state capital Hyderabad.

Lakhs of devotees come here to have a glimpse of the Brindavana or Vrindavana every year.